Pre Exposure Prophylaxis ( Prep ) - 1133 Words

Pre-exposure prophylaxis (PrEP) consists in the use of oral ART (either tenofovir alone, TFV, or in association with emtricibine, TFV/FTC) or topical vaginal TFV gel to prevent HIV transmission. This intervention was initially proposed following previous research that showed ART as an effective way to prevent transmission (i.e. prevention of mother-to-child-transmission, MTCT, treatment as prevention strategy, TaP, and in the context of post-exposure prophylaxis, PEP) (1, 6). Since 2012, following the results of RCTs showing PrEP to be efficacious against HIV transmission in different settings were, both the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO) have issue recommendations for its use on populations at increase risk for HIV infection. In this paper, I will discuss the scientific evidence on PrEP and particularities of its use among transgender women. (b) Targeted population A 2013 meta-analysis by Baral and colleagues indicated a 21.7% prevalence of HIV in this population in the US, which represents an odds 34.2 times that of the sexually active population (BARAL). Transgender women, an individual assigned as male early in life but who identifies as a woman, experience increased vulnerability to HIV infection that can be attributed to â€Å"multilevel, intersecting factors that also influence all stages of the HIV treatment treatment and care continuum†. (POTEAT). These factors include structural and interpersonal stigma,Show MoreRelatedPre Exposure Prophylaxis ( Prep ) Use1655 Words   |  7 PagesINTRODUCTION Pre-exposure prophylaxis (PrEP) use has proven to be efficacious in clinical study settings for the prevention of HIV infection; however, more knowledge is needed to inform best practice models for implementation of PrEP in high-risk urban populations. In upcoming years, we can expect many AIDS service organizations (ASOs) and community-based organizations (CBOs) to integrate PrEP into their clinics as a prevention tool. Demonstration projects are underway all over the country to studyRead MorePre Exposure Prophylaxis ( Prep ) For Hiv Prevention1201 Words   |  5 Pages Article Report Brent Henrikson Name: Universityâ€Æ' Article 1 Abstract â€Å"Pre-exposure prophylaxis (PrEP) for HIV prevention is a promising experimental approach currently being tested globally. A number of PrEP trials are evaluating the safety and effectiveness of PrEP in men who have sex with men (MSM) and other populations at risk for HIV, and results will be available from this first generation of efficacy trials over the next few years. Here we review the rationale for orally-administeredRead MoreLimitations Of Acquiring Data On Hiv1783 Words   |  8 Pages Preexposure Prophylaxis in Preventing HIV The most promising method of HIV prevention yet, especially in high-risk populations like the transgender female population, has been the use of preexposure prophylaxis, or PrEP for short. It is a daily oral medication that decreases HIV acquisition, and is for use by high-risk populations. It was recently approved by the U.S. Food and Drug Administration in 2013, which the CDC has also approved for use (7). The results of the first PrEP clinical trialRead MoreUptake Use And Effectiveness Of Pre-Exposure Prophylaxis In Hivya Essay1024 Words   |  5 Pagesdetermining the uptake, use and effectiveness of pre-exposure prophylaxis for HIV negative persons with partners living with HIV. Related to this study was another research conducted by the same researchers but this time they investigated antiretroviral prophylaxis for HIV-1 prevention among heterosexual men and women. In another study conducted by AIDS (London), the study was based on determining effectiveness and safety of HIV pr e-exposure prophylaxis for all populations. A study conducted by EmoryRead MoreUtilization Of Hiv Essay833 Words   |  4 PagesIntroduction This report is intended to provide an evaluation and assessment of Programs to Increase the Utilization of HIV Pre-Exposure Prophylaxis (PrEP) among Men Who have Sex with Mem (MSM) and Transgender Individuals and Collaborative Efforts to Metropolitan Statistical Area, offered by the International Black Women’s Congress (IBWC) in response to the request for proposal for The Virginia Department of Health, Division of Disease Prevention for the delivery of HIV services in the VirginiaRead MoreThe And Drug Administration Approved Truvada For Treating Hiv889 Words   |  4 Pagesbehind the Pre-Exposure Prophylaxis treatment, best known as PrEP, is the latest and, according to the Center for Disease Control (CDC), most efficient method of HIV prevention. However, the CDC still emphasizes on the importance of condoms and other prevention tools, even if the person is on PrEP. In 2004, The Food and Drug Administration approved Truvada for treating HIV infections. Eight years later, it debuted as the first drug (and still the only one) for pre-exposure prophylaxis (PrEP). EssentiallyRead MoreSouth Carolina Hiv / Aids Council Project Preplan Community Summit : Taking Action Changing Our Destiny1405 Words   |  6 Pagesdifferent walks of life: from seropositive and seronegative patients, to social workers, pharmacists, and doctors. Dr. Divya Ahuja from USC School of Medicine gave an overview of pre-exposure prophylaxis (PrEP). His platform was followed by multiple panel discussions regarding various questions and viewpoints about PrEP. Despite the awareness that has brought attention to HIV testing, and medicinal advancements that have made decreasing the rate of transmission possible, over 50,000 new HIV infectionsRead MoreThe Center For Disease Control And Prevention1562 Words   |  7 PagesFindings Furthermore, the Center for Disease Control and Prevention (CDC) reported that studies, as noted before, have shown PrEP reduces the risk of getting HIV through sexual intercourse by more than 90% and by more than 70% among populations who inject drugs when taken regularly. Gay or bisexual men increase their chance of being exposed to the virus if they have had anal sex without a condom, been diagnosed with an STD during the past 6 months or are in a relationship with an HIV-positive partnerRead MoreHiv And The United Kingdom1014 Words   |  5 Pagesthis public health problem. (Public Health England, 2014) 2.2. Truvada as PrEP In 2014, a pre-exposure prophylaxis (PrEP), Truvada, was introduced in the UK as a preventative method of HIV infection after it was made available in the United States in 2012. PrEP uses antiretroviral drugs (ART) to protect HIV-negative people from becoming infected with HIV; PrEP suppresses the virus and can reduce further transmission. PrEP was shown to be highly effective for gay men and MSM, as they are at greatestRead MorePractice Change : Use A Screening Tool For Identifying Candidates For Pre Exposure Prophylaxis1602 Words   |  7 PagesPractice Change: Use of a Screening Tool to Identify Candidates For Pre-Exposure Prophylaxis Introduction Despite advances in screening and treatment for human immunodeficiency virus (HIV) over the last 30 years, HIV remains a significant global issue (World Health Organization [WHO], 2015; Yagoda Moore, 2016). The United States (US) experienced a brief decline in new HIV cases, but total HIV incidence has failed to decrease meaningfully in the past 25 years (Yagoda Moore, 2016). According